Placebo Effect of Caffeine on Substrate Oxidation during Exercise

By using deceptive experiments in which participants are informed that they received caffeine when, fact, an inert substance (i.e., placebo), several investigations have demonstrated exercise performance can be enhanced to a similar degree as known dose. This ‘placebo effect’ phenomenon may part of the mechanisms explaining caffeine’s ergogenicity exercise. However, there is no study has established whether placebo effect also present for other benefits obtained with acute intake, such fat oxidation during Therefore, aim this investigation was investigate on Twelve young men participated double-blind cross-over experiment. Each participant completed three identical trials consisting step incremental test from 30 80% V.O2max. In two first trials, ingested either 3 mg/kg cellulose (placebo) or (received caffeine) randomized order. third trial, were had caffeine, but provided (informed caffeine). Fat rates derived stoichiometric equations. increased their rate over values at 30%, 40%, 50%, and 60% V.O2max (all p < 0.050). 50% 60%, 70% 0.050) placebo, while differences between versus caffeine. comparison (0.32 ± 0.15 g/min), maximal higher (0.44 0.22 g/min, = 0.045) (0.41 0.20 0.026) intensity Fatmax) (42.5 4.5, 44.2 9.0, 41.7 10.5% V.O2max, respectively, 0.539). conclusion, expectancy having produced effects than actually receiving intake substrate it used enhance reducing any risks health have.